Amylin Injectable Cagrilintide Demonstrates Weight Loss of 11.8% in Late Stage Trial: Novo Nordisk Update Patient Care Online Clinical trials of subcutaneous tirzepatide, retatrutide, and Download Scientific Diagram In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) CagrilintideSemaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial)
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cagrilintide phase 2 CagriSema in Adults With or Without Diabetes β REDEFINE 1 & 2 β’ π Cagrilintide 2.4 mg + Semaglutide 2.4 mg once weekly β’ π β20.4% weight loss (non-diabetic) & β13.7% (T2D)